therapeutics targeting cell adhesion
The Zonula Difference
Fibrosis is the process leading to the accumulation of collagen-based scars within tissues. Targeting cell adhesion represents a new approach to preventing fibrosis. Zonula is developing inhibitors of cell adhesion that turn off collagen production by cells called fibroblasts (shown in the picture).
Fibroblast adhesion is governed by N-cadherin, which can be thought of as a biological glue. Zonula's N-cadherin inhibitors disrupt fibroblast adhesion and collagen production by these cells.
n-cadherin controls fibrosis
zonula pipeline
